- Ezequiel Astacio
- Brandon Backe
- Mike Burns
- Roger Clemens
- Mike Gallo
- Chad Harville
- Brad Lidge
- Roy Oswalt
- Andy Pettitte
- Chad Qualls
- Russ Springer
- Dan Wheeler
- Arizona Diamondbacks
- Placed C Kelly Stinnett on the 15-day disabled list with a left wrist sprain and recalled C Koyie Hill from Triple-A Tucson.
- Boston Red Sox
- Designated LHP Alan Embree for assignment; Acquired OF Adam Hyzdu from the San Diego Padres for nonroster RHP Scott Cassidy; Acquired INF Tony Graffanino from the Kansas City Royals for nonroster OF Chip Ambres and LHP Juan Cedeno.
- Chicago Cubs
- Optioned OF Ben Grieve to Triple-A Iowa to make room for OF Jody Gerut to the 25-man roster.
- Cincinnati Reds
- OF Jason Romano has refused an outright assignment to Louisville and elected free agency.
- Colorado Rockies
- Activated OF Matt Holliday from the 15-day disabled list and optioned OF Ryan Spilborghs to Triple-A Colorado Springs.
- Florida Marlins
- Recalled RHP Travis Smith from Triple-A Albuquerque; Placed RHP Nate Bump on the 15-day disabled list, retroactive to July 17, with right shoulder inflammation.
- Houston Astros
- Optioned RHP Ezequiel Astacio to Triple-A Round Rock and recalled LHP Wandy Rodriguez from Triple-A Round Rock.
- Kansas City Royals
- Acquired nonroster LHP Juan Cedeno and OF Chip Ambres from the Boston Red Sox for INF Tony Graffanino and assigned Cedeno to Double-A Wichita.
- Los Angeles Dodgers
- Activated LHP Wilson Alvarez from the 15-day disabled list.
- New York Yankees
- Placed OF/DH Ruben Sierra on the 15-day disabled list with a strained left hamstring; Activated RHP Felix Rodriguez from the 15-day disabled list; Outrighted LHP Darrell May to Triple-A Columbus and recalled IF Andy Phillips from Triple-A Columbus.
- San Diego Padres
- Acquired RHP Scott Cassidy from the Boston Red Sox in exchange for OF Adam Hyzdu.
- San Francisco Giants
- Placed OF Marquis Grissom on rehabilitation assignment with Triple-A Fresno.
- Texas Rangers
- Recalled LHP C.J. Wilson from Double-A Frisco and optioned OF Jason Botts to Triple-A Oklahoma.
- Toronto Blue Jays
- Outrighted RHP Justin Miller to Triple-A Syracuse.